Decisions about whether or not to apply interventions should be based on the strength of available evidence.
Whether or not you decide to apply an intervention may depend on how sure you are about its positive and negative effects.
How sure you can be depends on whether claims about the effects of the intervention are based on a careful summary of studies comparing interventions, whether the studies were fair comparisons, how big the studies were, and how relevant the comparisons are to your context.
BEWARE of using evidence that you do not feel confident about.
REMEMBER to always consider the strength of evidence.